ISDIN Isdinceutics Retinal Advanced Night Serum – Retinaldehyde & Melatonin

Overview

ISDIN Isdinceutics Retinal Advanced Night Serum is a dual-phase facial serum designed to work while you sleep. Its split formula combines retinaldehyde with melatonin and bakuchiol, enhanced by a Soothing Complex that activates at the moment of application. Nightly use aims to address fine lines, loss of firmness, and dullness, with notable results reported after about a month of use.

What makes it different

• Dual-phase technology keeps actives separated until application, helping maintain stability and effectiveness.
• Retinaldehyde is a potent retinoid noted for youth-boosting skin renewal.
• Melatonin and bakuchiol support the skin's night-time renewal process while soothing the feel on application.
• Formulated for all skin types, including sensitive skin, and tested for compatibility across routines.

What you might notice

• Smoother texture and a more even complexion as the formula works through the night.
• Potential improvement in the appearance of fine lines and a firmer look over time.
• A lightweight, fast-absorbing finish that works well with your existing night regimen.

How to use

Apply a small amount after cleansing and before your moisturizer. Gently press into the face, avoiding the eye area. Allow the serum to absorb fully before continuing with your nightly routine. The two-phase formula activates on contact with skin, delivering actives as you rest.

Key ingredients at a glance

• Retinaldehyde: a powerful retinoid that supports renewal with a lower irritation profile for many users.
• Melatonin: a night-time antioxidant to complement renewal cycles.
• Bakuchiol: a plant-based option often used for gentle resurfacing.
• Soothing Complex: designed to improve comfort during application.

Note: results can vary by individual, skin type, and routine. If you have sensitive skin or are new to retinoids, consider patch testing and consulting a skincare professional.